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Improving mitochondrial NMN restores youth

2024-12-17 17:183170

Guardian of mitochondrial health

NMN is the world's first FDA-approved anti-aging substance. Mitochondria are the "power factories" in the cell, responsible for producing energy, and every molecule of oxygen that people need to breathe needs to be used in mitochondria.

Mitochondria have their own genetic material and genetic system, in addition to providing energy for cells, mitochondria are also involved in processes such as cell differentiation, cell information transmission and apoptosis, and have biochemical effects such as regulating cell growth and cell cycle.

What are mitochondria?

Mitochondria, a two-layer membrane-covered organelle present in most eukaryotic cells, are the structures in the cell that produce energy and are the main places of aerobic respiration in the cell, known as the "power house".

Its diameter is about 0.5 to 1.0 microns.

Mitochondria perform respiration within the cell, converting organic matter such as glucose into the energy molecule ATP (adenosine triphosphate), which provides energy for cells to carry out various metabolic activities and biosynthesis processes.

NAD+ is involved in hundreds of biochemical reactions within cells and is essential for maintaining normal cell function. It is the natural guardian in our body, silently guarding our health.

NAD+ is a compound composed of adenine and phosphoribose.

NAD+ plays an important role in energy metabolism and REDOX reactions in cells.

As we age, our levels of NAD+ in the body gradually decline, which leads to a decline in mitochondrial function and cellular aging.

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Mitochondrial function

Energy production:

Mitochondria provide energy to cells by converting organic matter into ATP through REDOX reactions during cellular respiration.

Fatty acid metabolism:

Mitochondria are involved in the oxidative metabolism of fatty acids, breaking them down into energy and metabolites.

Each molecule of pyruvate produced during glycolysis is actively transported across the mitochondrial membrane.

After entering the mitochondrial matrix, pyruvate is oxidized and combines with Coenzyme A to form CO2, reduced Coenzyme I and acetyl Coenzyme A.

Acetyl-coa is the primary substrate of the tricarboxylic acid cycle (also known as the "citric acid cycle" or "Krebs cycle").

The enzymes involved in this cycle are all free in the mitochondrial matrix except succinate dehydrogenase which is located in the inner membrane of mitochondria.

Calcium ion regulation:

Mitochondria can regulate the concentration of calcium ions in cells and participate in cell signaling and regulation.

In addition, mitochondria are also involved in the regulation of cell proliferation and metabolism, the synthesis of cholesterol and certain heme, the regulation of membrane potential, and the control of programmed cell death.

NMN and mitochondria

How does NMN affect mitochondrial function?

Studies have shown that NMN can improve mitochondrial function by increasing intracellular NAD+ levels.

NAD+ is a cofactor of many important enzymes in mitochondria, which is involved in the regulation of mitochondrial energy production and cell apoptosis.

By supplementing NMN, the intracellular NAD+ level can be increased, thereby improving mitochondrial function and increasing the energy production and survival ability of cells.

Efficiently supplement NAD+

NAD+ loss is the internal root of early aging

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The high-luxury combination effectively supplements NAD+

NMN also has antioxidant and anti-inflammatory effects, which also help protect mitochondria from damage.

Mitochondria are the most important source of free radicals in cells, and the accumulation of free radicals can lead to oxidative damage of mitochondrial DNA and membrane, and then affect mitochondrial function.

The antioxidant effect of NMN can reduce the production of free radicals and protect mitochondria from oxidative damage.

NMN can also suppress the inflammatory response and reduce the negative effects of inflammation on mitochondria.

With age, NAD+ levels decline, which can lead to decreased mitochondrial function and disrupted energy metabolism.

NMN supplementation can increase NAD+ levels, restore the balance of mitochondrial function and energy metabolism, and help maintain the health of cells and the whole body.

General junction

There is a close relationship between NMN and mitochondria.

It can improve mitochondrial function by increasing intracellular NAD+ levels, enhancing the energy production and survival of cells.

NMN also has antioxidant and anti-inflammatory effects that help protect mitochondria from damage.

NMN has great potential in the field of anti-aging and may become an important substance to delay aging and improve the quality of life.

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