According to an agency survey, it is found that many entrepreneurs and entrepreneurs work far more than normal, more than half of the people work more than 12 hours, some of them even work as long as 16 hours, long-term in a state of high load.
This constant overwork poses a threat to one's health.
Supplementing NMN, a precursor to NAD+, is considered an important strategy for relieving fatigue, a view supported by scientific research experiments.
To understand the mechanism behind this, we need to have a deep understanding of cellular metabolism.
Mitochondria are the energy factories of the body
The energy of the body comes from the cells, and the energy of the cells comes from the mitochondria in the cells.
The human body is made up of 6 billion trillion cells, and it can be said that the health of the cells determines the health of the human body.
The ability of cells to function properly depends on their ability to metabolize, and 95% of the energy needed for this process is provided by mitochondria, the energy factories inside the cell.
Mitochondria synthesize adenosine triphosphate (ATP), which is the direct source of energy for cells.
Mitochondria not only provide energy, but also regulate the process of cell growth and apoptosis.
In order to maintain vitality and vigorous energy throughout the day, mitochondria need to function efficiently, driving the active work of the entire body mechanism.
If mitochondrial function is damaged, resulting in insufficient cell energy supply, communication between cells will be interfered with, which may not only cause various health problems, but also may accelerate the aging process of the body.
NAD+ is a key factor affecting mitochondrial function
After understanding mitochondria, the next step is to explore the factors that affect their internal function.
Mitochondrial dysfunction can be caused by a variety of factors, one of the key factors being the deficiency of nicotinamide adenine dinucleotide (NAD+).
NAD+ plays a crucial role in the energy production and cellular function of mitochondria, it is a key enzyme in the production of adenosine triphosphate (ATP), which is a central component in the cellular respiration process.
Every cell needs a large amount of ATP to maintain its function, and NAD+ is the assistant that helps cells produce this energy.
In a study published in 2015, scientists pointed to the absence of NAD+ as an important factor in mitochondrial abnormalities.
In a 2012 study led by Professor Shinichiro Imai of the University of Washington in the United States, he delved into the "dynamic regulation of NAD+ metabolism in mitochondria" and confirmed the close link between mitochondrial function and NAD+ levels.
NAD+ is the key to inhibiting aging
After the age of 35, the content of NAD+ in the human body will decline rapidly, and the reduction of the content of NAD+ in cells will in turn lead to the decline of DNA repair ability, accelerate the accumulation of DNA damage, and then lead to the further reduction of the content of NAD+, forming a vicious cycle of faster and faster aging.
By maintaining sufficient NAD+ content in cells to break this vicious cycle, maintain the ability of DNA self-repair, so that the DNA damage caused by age can be effectively repaired, and inhibit the key to aging.
So what affects our mitochondrial metabolism, or NAD+ levels?
With the increase of age, the level of NAD+ in the cell is greatly decreased.
As a direct result, we will feel a noticeable decline in energy and physical strength.
NMN increases the body's NAD+ levels
As a direct precursor of NAD+, NMN can effectively increase the content of NAD+ in the body, which has been proved by numerous studies to be essential for enhancing the function of mitochondria.
In particular, in 2020, a research team from the University of Minnesota published research results that clearly pointed out the positive role of NMN in improving mitochondrial function.
The study focused on a type of cell that is extremely dependent on mitochondria - retinal pigment epithelial cells (RPE) - which are essential for maintaining vision.
Since RPE cells are almost entirely dependent on mitochondria for energy, these cells may die rapidly if mitochondrial function is impaired, such as due to decline in function due to aging, which in turn may lead to age-related macular degeneration.
The researchers found that NMN comprehensively improved the mitochondrial function of RPE, and the effect time was very fast, able to reach a peak effect within 24 hours after use.
This improvement is mainly achieved by increasing the production capacity of ATP.
In the practical application of NMN, this rapid energy boost can also be clearly felt.
After many people supplement NMN, the cell energy level is rapidly increased, so it seems to return to the energetic young state overnight.
NMN- The "ceiling" of the anti-aging boundary
GSHWORLD NMN is a kind of powder NMN that is easy to absorb and has a high conversion rate. The oral powder is directly absorbed by the abundant capillaries and oral mucosa under the tongue and acts on the whole body quickly. After a few minutes, it is converted into NAD by the body for continuous absorption, faster conversion and less metabolic loss to the digestive tract or liver.
Changes in different time periods after NMN administration:
1: Take ten days: the spirit becomes better, not easy to fatigue, physical strength increases, appetite increases, sleep quality improves.
2: Take it for one month: nail growth rate increases, hair loss decreases, hair growth accelerates, energy improves, hangover function improves, vision improves, weight loss.
3: Take for two months: flexible body, improved sleep quality, overnight to dawn, not easy to wake up, menopausal symptoms relieved, skin better, and smooth and delicate, wrinkles reduced, lightened, facial sagging improved, physiological more regular, sexual desire enhanced.
4: about three months of use: regular work and rest, wrinkles, law lines significantly improved, face rosy and shiny, improve blood pressure, blood lipid, blood sugar, constipation improved.
5: Take about six months: physical and mental improvement is obvious, skin is better, more shiny. White hair decreased, black hair increased.
6: Taking for about eight months: energetic, not easy to fatigue, muscle tissue is more powerful, the growth rate of black hair is faster, and the gastrointestinal function is improved. Restore fertility in middle-aged women and improve oocytes.
NMN usage and dosage:
Take 2-4 tablets daily for people over 50 years old and 1-2 tablets daily for people under 50 years old before meals.
There is no mandatory dosage of NMN, due to individual differences, the specific dosage can be increased or decreased according to personal experience.
Before exercise, before drinking, when tired, you can increase the dosage.
