Among the many studies of NMN, there are three most surprising effects.
Improve sleep quality
The body clock regulates important circadian rhythms such as sleep and wake cycles.
NMN is involved in regulating the expression of clock genes, making the clock more stable and accurate.
For example, it can affect the stability and activity of core clock proteins such as PER and CRY, allowing the body's sleep and wake cycles to better synchronize with the natural circadian rhythm, thereby improving sleep quality.
Melatonin is an important hormone that regulates sleep, and NMN can promote the secretion of melatonin by increasing the level of NAD+ in the body and activating enzymes related to melatonin synthesis, such as arylalkylamine n-acetyltransferase (AANAT), so as to help people more easily enter a deep sleep state and reduce the number of times they wake up at night.
Improve exercise endurance
During exercise, the body needs a lot of energy to maintain muscle contractions and bodily functions.
NMN can increase the level of NAD+ within cells, which in turn activates the function of mitochondria, enabling cells to produce energy more efficiently and provide more ATP to muscles, thereby enhancing exercise endurance.
For example, in aerobic exercise, people who take NMN supplements can maintain a longer state of exercise than those who do not take them, and the time of fatigue is significantly delayed.
Muscles will be damaged after exercise and need to be repaired in time to become stronger.
By activating longevity proteins such as SIRT1, NMN promotes the proliferation and differentiation of muscle stem cells, accelerates the repair process of muscle injury, helps new muscle tissue growth, reduces muscle fatigue and soreness, and enables people to recover from high-intensity exercise faster and improve subsequent exercise performance.
Enhance skin health
Collagen is a key protein in maintaining skin's elasticity and firmness.
By increasing the level of intracellular NAD+, NMN activates the relevant signaling pathway, promotes the synthesis of more collagen by fibroblasts, reduces the generation of wrinkles, makes the skin more smooth and delicate, and enhances the skin firmness and elasticity.
The skin is exposed to the external environment for a long time and is susceptible to free radical attack and inflammation, leading to skin aging and various skin problems.
NMN has a strong antioxidant capacity, it can activate the antioxidant enzymes in the cell, such as superoxide dismutase (SOD), remove free radicals, reduce the damage of oxidative stress on the skin.
NMN can also inhibit inflammatory response, reduce the release of inflammatory factors, improve the inflammatory state of the skin, and play a certain role in the adjuvant treatment of some skin inflammatory diseases such as acne and eczema.
